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Can we finally get ahead of drug shortages?

In this episode of Denatured, Christina Smolke, co-founder & CEO at Antheia and Kyle Pudenz, SVP and head of data & AI product at Cencora...
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Industry News

Brewing the Future of Medicine

From their early days working together at Caltech to building a company that is bringing groundbreaking science into commercial reality, Christina Smolke, Co-Founder & CEO...
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Newsletters

From micrograms to metric tons: Antheia’s scaling journey

Antheia has secured a conditional loan commitment of up to $80 million from the U.S. Department of War’s Office of Strategic Capital (OSC) to onshore...
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Industry News

How to tell if your scientific breakthrough can be a viable business

Scientific research and starting a company require very different skills, but they have at least one thing in common: They both require years of hard...
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Industry News

Antheia lands $80M conditional loan from Trump administration to onshore drug manufacturing

Next-gen manufacturer Antheia is teaming up with the U.S. Department of War to build out its infrastructure and onshore the U.S. drug supply chain....
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Industry News

Antheia gets $80M conditional DOD loan to onshore to the US

Biosynthesis manufacturer Antheia has won a conditional loan of $80 million from the US Department of Defense to help boost the domestic production of generic...
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Adam Takos, PhD

Head of Drug Innovation and Managing Director, Singapore

Adam has spent two decades driven by a fascination with how we can harness biology to solve complex challenges. His journey has been a rewarding evolution—from making fundamental discoveries in plant specialized metabolism to leading industrial programs in metabolic engineering and drug discovery. Beyond the technical work, Adam is an advocate for “no-fear-of-failure” team cultures. Having worked across three countries, he values the diverse perspectives that drive innovation and help us turn ambitious research into practical, life-saving solutions.

Chris Savile, PhD

Head of Business Development and Partnerships

Chris has spent the past 20 years focused on the development and commercialization of biomanufacturing processes across multiple sectors and has spent his recent career focused on identifying high-value commercial opportunities and building strategic partnerships in pharma, food, and health and wellness. Prior to joining Antheia, he was CEO at Willow Biosciences, executive director, commercial operations at Intrexon, and associate director, business development and senior scientist, R&D at Codexis. Chris holds a PhD in organic chemistry from McGill University.

Dr. Stefan Bauer

Head of Analytical Development

Stefan is a senior biotechnology leader in analytical chemistry and a passionate scientific and technical expert in analytical methods and principles, especially chromatography and mass spectrometry, using an extensive range of instrumentations for a variety of analytes in complex matrices, such as microbial fermentations. With a 20-year career-long commitment to high quality standards, focusing on optimizing and simplifying workflows, he excels at developing high-throughput methods that drive efficiency, cost savings, operational excellence, and scientific innovation. Previously, he led the bioanalytical teams at UC Berkeley, Zymergen, Perfect Day, Novonutrients, Inscripta, and Manus.

Andrew Saarni

Head of Fermentation Process Development & Scale-Up

Andrew is a strategic bioprocess leader with over a decade of experience guiding fermentation process development and scale-up efforts from early-stage R&D through commercial deployment for small molecules, proteins, and now, vital alkaloid medicines. He has a proven track record of aligning technical execution with business strategy, driving technology transfer and manufacturing readiness at domestic and international CDMOs, and building fermentation infrastructures that deliver precision, throughput, and reproducibility. Before Antheia, he was Director of Fermentation at Geltor and a Senior Fermentation Engineer at Geno. He currently leads Antheia’s global fermentation scale-up efforts to secure next-generation supply chains for critical medicines.

Richard Sherwin

Head of Commercialization

Richard is an industry veteran with more than 30 years of experience in the KSM, API, and intermediate markets. He is responsible for leading the commercialization and revenue generation for Antheia’s robust pipeline of products. Richard brings an exceptional track record of leading international sales teams, driving revenue growth, building strategic partnerships, and delivering innovative products to market, including ANDA and NDA developments. Richard led commercial efforts at some of the leading global pharmaceutical companies and most recently, built his own consultancy business advising a range of clients, including $1B divisions of major multinationals.

Appropriate regulatory submissions will be prepared and submitted to support Antheia’s customers who need to reference and access necessary process-related information.

Yihui Zhu, PhD

Head of Fermentation

Yihui leads the fermentation team at Antheia. With over 25 years of hands-on experience in the field, he brings in-depth knowledge and expertise in microbial metabolism and fermentation process development. He is also skilled in developing comprehensive fermentation data collection, analysis, and visualization systems. Prior to joining Antheia, he served as a fermentation lead at Intrexon and Codexis where he successfully built fermentation labs and teams and led multiple biofuel and biochemical projects to reach stretch milestones and tech transfer. Yihui is passionate about the potential of fermentation and is dedicated to advancing the field through innovative research and development.

Audrey Wang

Head of Financial Planning and Analysis

Audrey leads financial planning and analysis at Antheia. With an MBA from Washington University in St. Louis, Audrey is passionate about leveraging financial analysis, digital technology, and data analytics to guide companies in making optimal investments and strategic business decisions. Audrey has a decade of experience in helping companies solve unique problems and creating long-term impact with unconventional approaches. Before joining Antheia, she was at Vir Biotechnology and Merck where she led various FP&A workstreams, including investment valuation, asset prioritization, and manufacturing sites operation finance support. Audrey completed CFA Level II and passed the U.S. CPA exam in 2011.

Antonij Tjahjadi, CPA

Head of Accounting

Antonij Tjahjadi leads accounting at Antheia and holds active CPA license. He joined Antheia with more than 20 years of experience in corporate accounting, bringing deep expertise in ramping up accounting operations for start-up companies, SEC reporting/technical accounting, and SOX implementation efforts. Before joining Antheia, he held various leading roles in both public and private company settings, including directing accounting functions at Ambys Medicines, where he successfully implemented Netsuite with Point Purchasing integration and set up various accounting policies and processes, and played a key role in the initial public offering of Nutanix, Inc.

Ken Takeoka

Head of Biology

Ken leads the Biology team at Antheia, which incorporates both strain and protein engineering functions. He has more than 16 years of experience in the synthetic biology field, working with leading companies, including Amyris and Novartis. One of his passions is molecular biology tool development and he previously worked to build the foundation for the automated strain engineering pipeline at Amyris. At Novartis, he modernized the molecular biology techniques and established a platform to model mechanisms of antibiotic resistance in a range of organisms.

Suzanne Sato

Head of Downstream Processing

Suzy leads downstream chemistry processes at Antheia. She has 19 years of experience in process development, including route development through synthetic chemistry and scale-up of small molecule APIs for GPCR targets under cGMP for Phase I-III trials. Before joining Antheia, Suzy led a full DSP team at Amyris where she successfully pivoted developments from biofuels hydrocarbon products to pharmaceutical intermediate, flavor, fragrance and nutraceutical products. She led a team that scaled 11 products and took five products to commercial manufacturing.

Farrah Pulce, PMP

Head of Project Management

Farrah leads program and project management at Antheia. She has over 20 years of experience leading program and project management, operations, and engineering for companies across the CPG, aerospace, and automotive industries. Prior to joining Antheia, Farrah implemented and led the sustaining program management team at Impossible Foods. She also led product operations, project management, and cost optimization at Blue Bottle Coffee and Tyson Foods to develop and commercialize new products. As a certified project management professional (PMP), Farrah has a proven record of successful project delivery, improving project management practices, and building collaborative teams.

Jordyn Lee

Head of Communications

Jordyn leads communications and external affairs at Antheia. She brings a decade of multidisciplinary communications experience in helping companies make complex science and technology accessible to broad audiences, all while maintaining technical accuracy and integrity. She has a passion for visionary storytelling and translating impact across the entire communications ecosystem – her work has spanned from public relations to corporate communications to marketing. Jordyn has served as an advisor to a number of different life sciences companies and most recently led corporate communications at Amyris.

Ben Kotopka, PhD

Head of Data Science

As Head of Data Science at Antheia, Ben manages in-house software development and external partnerships for storing and interpreting research data, executing bioinformatics analyses, and streamlining business processes. Prior to Antheia, Ben worked as an academic researcher at the intersection of machine learning, bioinformatics, and synthetic biology. Following this, as an entrepreneur and consultant, he developed and deployed data science solutions for biotechnology applications ranging from metabolomics-driven compound discovery to MRI segmentation.

Guerin Kob

Head of Supply Chain

Guerin is responsible for leading the design, development, management and improvement of Antheia’s end-to-end global supply chain. He has over 15 years of experience leading high-performing supply chain and procurement teams at leading biotechnology and specialty chemical companies, with extensive experience in process development and end-to-end supply chain optimization. Prior to joining Antheia, Guerin served as Senior Director of Global Supply Chain for Sumitomo Chemical’s biotechnology division with Valent Biosciences, where he led the end-to end supply chain including procurement, logistics and distribution, integrated business planning, materials management, customer service, and supply planning functions globally.

Eric d'Esparbes

Chief Financial Officer

Eric is a seasoned executive with 30 years of experience serving as the Chief Financial Officer for both private and public companies across various industries, including pharmaceuticals, biotechnology, diagnostics, and energy. He has successfully built and managed finance organizations for companies with a broad international footprint and annual sales of up to $3.5 billion. Eric has a proven track record in investor relations, capital raising to support organic growth and strategic partnerships/M&A, optimizing capital structures, and managing IPO processes, including transitions from private to public companies.

Jesse Ahrendt

Head of Quality Assurance and Regulatory Affairs

Jesse has more than 25 years of experience in regulatory affairs, quality systems, manufacturing quality, and regulated industries, ranging from early- to late-stage pharmaceuticals, biomanufacturing, consumer care, and medical devices. He has supported global product launches and the underlying quality supply chain components in industries that require strict adherence to internationally accepted quality standards. Before Antheia, he led quality efforts at Zymergen and Sandoz, and supported many global pharmaceutical companies during his time in Biotech Consulting at NSF International, all to bring quality to the forefront in manufacturing, standardize global processes, and support customer regulatory requirements.

Heidi Pucel

Chief People Officer

Heidi is a results-driven human resources executive and HR business partner who leverages decades of experience in empowering, motivating, and inspiring to drive transformation within high-performing and rapidly-growing workforces. A certified executive coach and passionate advocate for people-oriented solutions, Pucel serves as a partner to executive teams to design programs that support employee development, engagement, and recruitment and retention. Pucel most recently served as Chief People Officer for Countsy, where she worked as an interim HR executive for clients in the biotechnology and software industries, such as Ceribell and Tune Therapeutics.

Zack McGahey

Chief Operating Officer

Zack is a leading executive in operations management, specializing in bioprocess engineering and manufacturing management. He has over 20 years of experience leading manufacturing functions for companies across the pharmaceutical, synthetic biology, diagnostics, and automotive industries. Before joining Antheia, Zack was VP of manufacturing and capex project management at Zymergen. He also gained experience managing commercial scale facilities operations for Tesla, where he was responsible for managing 10 million square feet of factory, lab and warehouse space during the Model 3 ramp.

Kristy Hawkins, PhD

Co-Founder & CSO

Kristy has over 20 years of experience in the field of synthetic biology, focusing on yeast metabolic engineering for the production of small molecules. She did the founding work on the benzylisoquinoline alkaloid pathway during her graduate studies and gained valuable industry experience at Amyris and Lygos. Kristy is an expert in tool development, high-throughput screening, and host strain and heterologous pathway engineering.

Christina Smolke, PhD

Co-Founder & CEO

Christina is a pioneer in synthetic biology and metabolic engineering, where she has over 20 years of experience. As Professor of Bioengineering and Chemical Engineering at Stanford University, her laboratory led the breakthrough research to engineer baker’s yeast to produce some of the most complex and valuable medicines known. Under her leadership, Antheia’s advanced biosynthesis platform enables new possibilities for drug discovery and efficient, sustainable, transparent, and on-demand drug manufacturing at scale. Her vision and accomplishments have garnered numerous awards, including the Chan-Zuckerberg Biohub Investigator, NIH Director’s Pioneer Award, Nature’s 10, Novozymes Award for Excellence in Biochemical Engineering, and TR35 Award.

Antheia Secures $80Mn Conditional Funding Commitment from Department of War’s Office of Strategic Capital

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Appropriate regulatory submissions will be prepared and submitted to support Antheia’s customers who need to reference and access necessary process-related information.